Determination of Phytochemical Analysis and antibacterial activity of Pedalium murex against diabetic wound pathogenisis

Abiraj | Renugadevi

Pedalium | phytochemicals

Vol: 11; Iss. 5; May. 25 | ISSN: 2454-5422

The increasing prevalence of diabetes worldwide has led to a rise in diabetic-related complications, including chronic wounds that are highly susceptible to infection. The search for effective natural antimicrobial agents to treat diabetic wound pathogens has led to the exploration of various plant extracts. This study aims to evaluate the phytochemical composition and antibacterial activity of Pedalium murex, a plant known for its medicinal properties, against common diabetic wound pathogens. The plant extracts were obtained using solvents of varying polarities and the phytochemical analysis was carried out to identify the presence of bioactive compounds such as alkaloids, flavonoids, saponins, and tannins. Antibacterial activity was assessed using the disc diffusion method against pathogens including Escherichia coli, Staphylococcus sp, Salmonella sp and Klebsiella sp. The results showed that Pedalium murex extracts exhibited significant antibacterial activity. The phytochemical profile revealed the presence of several compounds known for their antimicrobial properties. These findings suggest that Pedalium murex could be a potential source of natural antibacterial agents for the treatment of diabetic wounds. Further studies on its mechanism of action and in vivo efficacy are recommended to confirm its therapeutic potential.

Renugadevi, PG & Research Department of Microbiology, V.H.N. Senthikumara Nadar College (Autonomous), Virudhunagar, Tamilnadu, India