Human cytomegalovirus is the cause of human atherosclerosis
Authors
Ilija Barukčić
Keywords
Human cytomegalovirus | atherosclerosis
Publication Details
Volume: 6; Issue: 1; Jan-2020 | ISSN: 2454-5422
Abstract
Objective: Human cytomegalovirus (HCMV) infection has been supposed to play an important role in the pathogenesis of human atherosclerosis (AS). Although many authors proved the presence of viral DNA in arterial wall tissue, the role of HCMV in the origin and progress of atherosclerosis still remains unclear and no definite consensus has been reached. Whether HCMV may be involved in the development of AS has not yet been established.
Methods: The purpose of this study was to investigate whether HCMV and AS are causally related. The conditio sine qua non method, the conditio per quam method, the causal relationship and other methods were used to re-analyzed the data available.
Results: HCMV is a necessary condition of AS. HCMV is a sufficient condition of AS. There is a highly significant cause effect between a HCMV infection and AS. This review and meta-analysis results provide striking evidence that a HCMV infection and AS are causally connected.
Conclusions: In conclusion, a HCMV infection is the cause of AS.
