Antimicrobial and Anti-cancer Activity of Capsicum chinense Bhut Jolokia fruit: An In-vitro Analysis

Anantha Shibi et al.,

Capsicum chinense Bhut Jolokia fruit | phytochemicals

Vol: 3; Iss: 12; Dec 17 | ISSN: 2454-5422

The present study was aimed to estimate the phytochemical components and antimicrobial activity of Capsicum chinense Bhut Jolokia fruit extracts. In this investigation, the fruit extracts contained more numbers of phytochemical constituents and potent antimicrobial activity against pathogenic microorganisms. In addition it lays the ground for the new research that is testing new varieties of Capsicum for cytotoxic studies. The lung cancer (A549) cell lines were used to screen the in vitro anticancer challenging with the fruit extracts. Concentration ranges from 6.25 to 100 µg of fruit purified extracts were screened against (A549) cells. The anticancer activity of fruit extract was performed by 3-[4, 5–Di methyl thiazol-2-yl]-2, 5-diphenyltetrazolium Bromide (MTT) assay. The cytotoxicity was highly significant in the 100 µg concentration of fruit extract in the lung cancer (A549) cell lines. These results concluded that Capsicum chinense Bhut Jolokia fruit have good antimicrobial and cytotoxic effect which serve as an important source of pharmacological applications